KADAR IMUNOGLOBULIN E, JUMLAH EOSINOFIL PADA PENDERITA FILARIASIS DENGAN ELEFANTIASIS DAN PENDERITA FILARIASIS PASCATERAPI

Background: Filariasis is an infectious disease (Elephant Leg Disease) caused by Filaria worms that are transmitted by various species of mosquitoes. This disease is chronic (chronic) and if not treated can cause permanent disability in the form of enlargement of the legs, arms and genitals of both women and men. Worms Wuchereria bancrofti, Brugia malayi and Brugia lymphatic filariasis causes timori as living exclusively in the human body. Method:This study aimed to know the difference between total IgE levels and absolute number of eosinophils in patients with elefantiasis and filariasis filariasis patients post-therapy in the district Muaro Jambi.The location of the working area of research in PHC Kemingking In the Garden District Rajo Muaro Jambi by using cross sectional comparative study. The study population was all patients who are diagnosed filariasis with elefantiasis and filariasis patients diagnosed with post-therapy in Puskesmas Kemingking Muaro Jambi in Jambi Province. All of the sampled population with respect to inclusion and exclusion criteria. Status filariasis diagnosis obtained from peripheral blood examination. Total IgE levels obtained with laboratory examination with ELISA method and the absolute number of eosinophils obtained by laboratory tests using eosinophil kit. Processing and analysis of data using non-parametric statistical test Mann-Whitney test and Kolmogorov-Smirnov test. Results of research on total IgE levels filariasis patients with the highest examination results are elefantiasis 3560.5 IU / mL while the lowest 29.2 IU / mL filariasis patients with filariasis elefantiasis and obtained post-therapy mean total IgE levels amounted to 997.3 IU / mL and total IgE levels of patients filariasis highest post-therapy assessment was 4130.5 IU / mL while the lowest 19.2 IU / mL is obtained mean of 1744.6 IU / mL. Absolute number of eosinophils filariasis patients with the highest examination results Elefantiasis 103/?L was 13.1 while the lowest mean of 4.8 0.7 obtained 103/?L 103/?L and absolute number of eosinophils filariasis patients post-therapy results highest examination was 16.9 while the lowest 3.1 103/?L 103 / obtained a mean 5.7 mL 103/?L. There was no significant difference in total IgE levels in patients with elefantiasis and filariasis filariasis patients post-therapy in Jambi Province Muaro Jambi with P-value, its value (0.205)> ? (0.05). There was no significant difference in absolute absolute number of eosinophils in patients with elefantiasis and filariasis filariasis patients post-therapy in Jambi Province Muaro Jambi with P-value, its value (0.970)> ? (0.05)